Publications

Worker and Environmental Assessment of Potential Unbound Engineered Nanoparticle Releases, Phase II Final Report: Preliminary Control Band Development

Publication Information:

Cassucio, Gary, Randall Ogle, Linnea Wahl, Ron Pauer, “Worker and Environmental Assessment of Potential Unbound Engineered Nanoparticle Releases, Phase II Final Report: Preliminary Control Band Development,” RJ Lee Group, Inc., and Lawrence Berkeley National Laboratory, September 2009.

Year: 2009

Topics: EH&S, Government, Laboratory Services, Materials Characterization, Nano-characterization, Particle Characterization, Quality Control

http://www.lbl.gov/ehs/esg/

The Phase II study activities involved the development of preliminary control bands. Based on the characterization of the source material as described for the gold nanorods, a review of process activities, and an assumed toxicity, a table of risk attributes specific to the material was generated. The table of risk attributes for the gold nanorods is shown in Table 1. A preliminary control band was then established for this process, as shown in Table 2.

Table 1. Risk Attributes for Gold Nanorods

Risk Attribute

Gold Nanorods

Particle Size

Rod-shaped particles ~20 nanometers (nm) in diameter and ~50 nm in length; rounded and spherical particles were ~40-50 nm in diameter

Particle Morphology

Primarily rod-shaped particles; rounded and spherical particles; observed in clusters

Elemental Chemistry

SEM/EDS: Au; Si residue

Solubility (water)

Insoluble

Toxicity of Nanomaterial

High

Amount of Material Used

< 10 mg

Dustiness/Airborne Potential

Low

Number of People Doing the Work

1-3

Duration of Operation

< 10 min

Frequency of Operation

1-5 times/week

Table 2. Preliminary Control Bands for Gold Nanorods

Preliminary Control Bands for Gold Nanorods

Release/Exposure Probability 2
Worker/Environmental Hazard C
Preliminary Control Band II

A preliminary control level II (refer to Fig. 1) was assigned to this process based on the category 2 release/exposure probability and category C worker/environmental hazard. Lawrence Berkeley National Laboratory is performing research activities using this material with level II controls in place for this process. Thus, the current level of controls for this process conforms to the control level indicated by the preliminary control band.