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| Antineoplastic (Chemotherapy Drug) Surface Contamination Assessment Some chemotherapy drugs are carcinogenic or cytotoxic at trace levels so occupational exposure is a concern. There is a lack of standard methods for the collection or analysis of hazardous or cytotoxic drug samples. RJ Lee Group (RJLG) assessed antineoplastic (chemotherapy drug) surface contamination in a major New York hospital pharmacy and associated nursing area. Selected drugs were detected in quantifiable levels on most surfaces within the pharmacy buffer and ante areas. This is a "hot topic" in the field of hazardous drug exposures and studies are currently being conducted by the National Institute of Occupational Safety and Health (NIOSH) and others. RJLG's Dr. Farrell Melnick, has recently been appointed to the NIOSH Hazardous Drug Committee by Dr. John Howard, Director of NIOSH. |
| Applying Automation to Wear Debris Particle Characterization (ASTM-F 1877) for Spinal Implants Assessment of the wear of total intervertebral disc (IVD) prostheses is an essential component to the FDA approval process. RJ Lee Group (RJLG) experts have utilized automated Scanning Electron Microscope (SEM) technology and provided results over large sample populations in rapid turn-around-times. This automated method has allowed our experts to spend more time providing service to our clients to ensure satisfaction and reduce costs. |
| Apportionment of Ambient PM10 Using Scanning Electron Microscopy Ambient PM10 samples were collected from five locations in Corcoran, California as part of the Fall 2000 field program component of the California Regional Particulate Air Quality Study (CRPAQS). Ambient PM10 samples were also collected at a remote location to estimate regional influence on air quality in Corcoran. Source samples of geological material were collected from soil near the site of each ambient monitor. Scanning Electron Microscopy (SEM) analysis techniques were used by RJ Lee Group (RJLG) to evaluate the ambient PM10 and local soil samples. Individual particle species concentrations were compared between source and ambient samples to determine the principal contributing sources of PM10 and to assess the extent of contributions from nearby neighborhood, urban and regional sources. |
| Asbestos Air Concentration Analysis in Buildings Following San Francisco Earthquake On October 17, 1989, an earthquake struck the San Francisco Bay Area of California damaging many buildings. Because of the concern over the possible exposure to asbestos in the damaged buildings, building owners and managers hired RJ Lee Group (RJLG) to collect air samples in suspect buildings. Our experts analyzed a total of 419 air samples from 55 buildings (schools, universities, commercial / public, and residential buildings) using transmission electron microscopy (TEM) in accordance with the EPA AHERA and Level II analytical protocols. The results indicated that asbestos levels differed little from outdoor levels, even immediately after the earthquake. Exceptions to this were samples collected in the vicinity of debris clean-up and in the building undergoing abatement, which were higher than the indoor or outdoor samples. However, these samples generally had concentrations below the AHERA clearance levels and all were well below the OSHA action limit. |
| Asbestos Evaluation of EPA's Analytical Data from El Dorado Hills The EPA study, "El Dorado Hills, Naturally Occurring Asbestos Multimedia Exposure Assessment Preliminary Assessment and Site Inspection Report Interim Final" ("El Dorado Hills Study"), concluded that for the area studied, asbestos fibers are present in both the soil and background air and noted exposure to elevated concentrations of asbestos fibers in connection with activity-based monitoring. In September 2005, RJ Lee Group (RJLG) was contracted to conduct a peer review of the El Dorado Hills Study. Specifically, RJLG was asked to evaluate whether the air and soil data gathered and analyzed by EPA and the contracted laboratories support the published findings, and to assess the data collected using the latest science concerning asbestos fiber definition and whether or not there was significant exposure. Applying the latest scientific and definitional techniques, RJLG found that the El Dorado Hills Study showed no significant exposure to the specific type of amphibole asbestos fiber. |
